Product Description
Technical Details:
- Trade Name: Jevtana
- Ingredients: Cabazitaxel
- Manufacturer: Sanofi
- Type: Injection
- Power: 60 mg/1.5 ml
- Molecular Formula: C45H57NO14C3H6O
- Molecular Weight: 894.01 (for the acetone solvate) / 835.93 (for the solvent free)
- Solubility: Insoluble in water and soluble in alcohol.
- Form: White to almost-white powder
JEVTANA (cabazitaxel) injection is an antineoplastic agent belonging to the taxane class that is for intravenous use. It is prepared by semi-synthesis with a precursor extracted from yew needles.
The chemical name of cabazitaxel is (2,5,7,10,13)-4-acetoxy-13-({(2R,3S)-3[(tertbutoxycarbonyl) amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1-hydroxy-7,10-dimethoxy-9oxo-5,20-epoxytax-11-en-2-yl benzoate propan-2-one (1:1).
Cabazitaxel injection is indicated in combination with prednisone for the treatment of patients with metastatic castration-resistant prostate cancer previously treated with a docetaxel-containing treatment regimen.