Most research on glucosamine sulfate has measured its effectiveness on osteoarthritis of the knee. However, there is some evidence that it might also help osteoarthritis of the hip or spine. Some research suggests that glucosamine reduces pain of osteoarthritis in the knee about as well as the over-the-counter pain reliever acetaminophen (Tylenol). It also seems to reduce pain about as much as the nonsteroidal anti-inflammatory drugs (NSAIDs) ibuprofen (Motrin, Advil) and piroxicam (Feldene).
INDICATIONS : Glucosamine sulfate is taken by mouth for osteoarthritis, glaucoma, weight loss, joint pain caused by drugs,a bladder condition called interstitial cystitis, jaw pain, joint pain including knee pain, back pain, multiple sclerosis, and HIV/AIDS
SIDE EFFECTS :Glucosamine sulfate is LIKELY SAFE when used appropriately by mouth in adults.Glucosamine sulfate is POSSIBLY SAFE when injected into the muscle as a shot twice weekly for up to 6 weeks or when applied to the skin in combination with chondroitin sulfate, shark cartilage, and camphor for up to 8 weeks.